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Journal of Crohn's and Colitis: 9 (8)

Editor-in-Chief

Laurence J. Egan, Ireland

Associate Editors

Maria T. Abreu, USAShomron Ben-Horin, IsraelSilvio Danese, ItalyPeter Lakatos, HungaryMiles Parkes, UKGijs van den Brink, NLSéverine Vermeire, Belgium

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Published on behalf of

Pulmonary Crohn's disease: A rare extra-intestinal manifestation treated with infliximab

Natalia Pedersen, Dana Duricova, Pia Munkholm
DOI: http://dx.doi.org/10.1016/j.crohns.2009.03.007 207-211 First published online: 1 September 2009

Abstract

Crohn's disease is a chronic inflammatory bowel disease often presenting with extra-intestinal manifestations. However, pulmonary involvement is quite rare. We report a case of Crohn's disease with pulmonary extra-intestinal manifestation (bronchiolitis obliterans organizing pneumonia-like changes) treated with infliximab. Furthermore, we present an overview of cases of inflammatory bowel disease with lung involvement, treated with tumor necrosis factor-α antagonists. In this case, when infliximab was given, a significant resolution of the pulmonary changes was achieved.

Keywords
  • Crohn's disease
  • Pulmonary extra-intestinal manifestation
  • Infliximab
  • Abbreviations
    BOOP
    Bronchiolitis obliterans organizing pneumonia
    CD
    Crohn's disease
    IBD
    Inflammatory bowel disease
    UC
    Ulcerative colitis
    TNF-α
    Tumor necrosis factor-α
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