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Journal of Crohn's and Colitis: 9 (4)


Laurence J. Egan, Ireland

Associate Editors

Maria T. Abreu, USAShomron Ben-Horin, IsraelSilvio Danese, ItalyPeter Lakatos, HungaryMiles Parkes, UKGijs van den Brink, NLSéverine Vermeire, Belgium


Published on behalf of

Managing the long term care of inflammatory bowel disease patients: The cost to European health care providers

James Buchanan , Sarah Wordsworth , Tariq Ahmad , Angela Perrin , Severine Vermeire , Miquel Sans , Jenny Taylor , Derek Jewell
DOI: http://dx.doi.org/10.1016/j.crohns.2011.02.005 301-316 First published online: 1 August 2011


Background and aims: Inflammatory Bowel Disease (which includes Crohn's Disease and Ulcerative Colitis), is a chronic condition characterised by substantial morbidity. Inflammatory Bowel Disease patients are considered expensive to manage, hence accurate estimates of care costs are crucial to help healthcare providers plan clinical management. The aim of this study is to estimate the cost of care for Crohn's Disease and Ulcerative Colitis patients in the United Kingdom and Western mainland Europe.

Methods: Decision models were built to simulate the natural disease history of Crohn's Disease and Ulcerative Colitis, informed by United Kingdom and European clinical pathways. A healthcare provider perspective was adopted, model inputs were informed by published sources and expert opinion, and UK healthcare costs were used (2008 prices). Cohorts of 25 year old patients presenting with symptoms of varying severity were modelled over ten years, and annual treatment costs calculated per patient.

Results: The average annual cost of care per Crohn's Disease/Ulcerative Colitis patient was £631/£762 (United Kingdom) and £838/£796 (Europe). Most costs were incurred immediately following diagnosis, particularly in European Crohn's patients, reflecting the earlier use of more aggressive treatments. Surgery, hospitalisation, and the use of biological therapies and mesalazine (in Ulcerative Colitis) were key cost drivers. The total annual cost to the United Kingdom National Health Service of caring for Inflammatory Bowel Disease patients was estimated to be £131 million.

Conclusions: This study confirms that Inflammatory Bowel Disease patients are expensive to manage and illustrates the importance of differentiating between alternative clinical management scenarios.

  • Inflammatory bowel disease
  • Ulcerative colitis
  • Crohn's disease
  • Health economics
  • Costs
  • Abbreviations:
    Crohn's Disease
    Inflammatory Bowel Disease
    National Health Service
    Probabilistic Sensitivity Analysis
    Ulcerative Colitis
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