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Journal of Crohn's and Colitis: 9 (4)

Editor-in-Chief

Laurence J. Egan, Ireland

Associate Editors

Maria T. Abreu, USAShomron Ben-Horin, IsraelSilvio Danese, ItalyPeter Lakatos, HungaryMiles Parkes, UKGijs van den Brink, NLSéverine Vermeire, Belgium

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Published on behalf of

Microscopic colitis: Current status, present and future challenges
Statements of the European Microscopic Colitis Group

A. Münch , D. Aust , J. Bohr , O. Bonderup , F. Fernández Bañares , H. Hjortswang , A. Madisch , L.K. Munck , M. Ström , C. Tysk , S. Miehlke , European Microscopic Colitis Group (EMCG)
DOI: http://dx.doi.org/10.1016/j.crohns.2012.05.014 932-945 First published online: 1 October 2012

Abstract

Microscopic colitis (MC) is an inflammatory bowel disease presenting with chronic, non-bloody watery diarrhoea and few or no endoscopic abnormalities. The histological examination reveals mainly two subtypes of MC, lymphocytic or collagenous colitis. Despite the fact that the incidence in MC has been rising over the last decades, research has been sparse and our knowledge about MC remains limited. Specialists in the field have initiated the European Microscopic Colitis Group (EMCG) with the primary goal to create awareness on MC. The EMCG is furthermore a forum with the intention to promote clinical and basic research. In this article statements and comments are given that all members of the EMCG have considered being of importance for a better understanding of MC. The paper focuses on the newest updates in epidemiology, symptoms and diagnostic criteria, pathophysiology and highlights some unsolved problems. Moreover, a new treatment algorithm is proposed on the basis of new evidence from well-designed, randomized control trials.

Keywords
  • Microscopic colitis
  • Collagenous colitis
  • Lymphocytic colitis
  • Budesonide
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